下肢静脉曲张是血管外科常见疾病之一。手术是下肢静脉曲张的常用治疗手段,主要分为传统结扎剥脱术及微创腔内治疗技术。腔内热消融(Endovenous Thermal Ablation, EVTA)已逐步发展为一线治疗选择,但存在手术时间长、需要肿胀麻醉、热损伤相关并发症等问题。近十年以来兴起的氰基丙烯酸酯胶消融(Cyanoacrylate-glue Ablation, CAA)治疗下肢静脉曲张具有微创便捷、非热非肿胀、并发症发生率低、中远期闭合率高等优势,未来有望成为主流选择。本文就氰基丙烯酸酯胶(Cyanoacrylate Glue, CG)的发展、作用原理、疗效以及应用特点等方面进行综述。Lower extremity varicose veins are one of the common diseases in vascular surgery. Surgery is a common treatment, mainly categorized into traditional ligation-stripping and minimally invasive endovenous techniques. Endovenous thermal ablation (EVTA) has gradually developed into a first-line treatment option, but there are some problems, such as long operation time, need for tumescent anaesthesia and thermal injury related complications. In the last decade, Cyanoacrylate-glue Ablation (CAA) has emerged as a treatment choice for lower extremity varicose veins. CAA has the advantages of minimally invasive and convenient, non-thermal and non-tumescent, low incidence of complications, high medium and long-term closure rate, and is expected to become the mainstream choice in the future. This paper reviews the development, principles, curative effect and application characteristics of Cyanoacrylate Glue (CG).
以病例，问题为中心教学（ Case based learning/problem-based learning, CBL/PBL ）是在传统医学教学模式基础上发展而来的新兴教学方式。从2006年起，重庆医科大学附属第二医院血管外科将CBL／PBL全面导入临床教学中，为量化教学效果对比评价了讲授式教学法（Lecturebased learning,LBL）与CBL／PBL。教学结果显示，CBL／PBL对提高学生自主学习能力和临床实习质量有积极作用，但在现有考核体系下，其优势难以完全发挥。
