目的:基于R语言平台分析国家专利复方治疗骨结核的用药规律,为骨结核的中医药治疗提供参考依据。方法:检索“国家知识产权局–中国专利公布公告”网站中治疗骨结核的复方专利数据,采用Excel软件提取纳入文献信息并进行四气五味归经统计,利用R语言进行频数统计、关联规则分析、聚类分析。结果:共纳入70首专利复方,共包含药物180味,用药频数大于10的药物分别是当归、甘草、全蝎、蜈蚣、黄芪、鳖甲、没药、乳香、穿山甲、白芨。药物药性以温、寒、平性为主,药味以甘、辛、苦味为主;归经以肝、脾、肾经为主。关联规则分析显示获得以当归、甘草、全蝎、蜈蚣、熟地、乳香、没药为核心的药物组合;层次聚类分析得到4类药物组合。结论:分析强直性脊柱炎临床用药的常用组合规律,为临床治疗强直性脊柱炎提供用药思路。Objective: To analyze the medication rule of national patent compound treatment based on R language platform and provide a reference for TCM treatment of bone tuberculosis. Methods: We searched the compound patent data for the treatment of bone tuberculosis in the website of “State Intellectual Property Office-China Patent Announcement”, extracted the included literature information and collected the four gas and five taste statistics, and used frequency statistics, association rule analysis and cluster analysis in R language. Results: A total of 70 patented compounds were included, including 180 drugs with drug frequency greater than 10 were angelica, licorice, scorpion, centipede, Astragalus, turtle nail, myrrh, frankincense, pangolin and Bletilla striata. Warm, cold, plain and sweet, spicy and bitter;mainly liver, spleen and kidney. The association rule analysis showed that the drug combinations with angelica, licorice, whole scorpion, centipede, ripening, frankincense and myrrh were obtained;the hierarchical clustering analysis obtained four types of drug c
目的:颈性眩晕是一种常见的临床病症,其病理机制复杂,涉及颈部结构的异常和神经功能失调。本文详细阐述了颈性眩晕的定义、分类及发病机制,以明确其病理基础。随后,文章深入探讨了针灸和推拿手法治疗颈性眩晕的原理与方法,分析了两种传统中医治疗方法的理论基础和具体操作步骤。在此基础上,本文进一步探讨了针灸联合推拿手法治疗颈性眩晕的临床研究,包括研究设计、实施过程以及结果的分析与讨论。研究结果表明,针灸和推拿手法的联合应用在治疗颈性眩晕方面具有显著的疗效,能够显著改善患者的症状和生活质量。本文的研究为颈性眩晕的临床治疗提供了新的视角和方法,对于推动中医传统治疗方法在现代医学中的应用具有重要意义。Objective: Cervical vertigo is a common clinical condition with complex pathological mechanisms, involving abnormalities in neck structure and neurological dysfunction. This article elaborates on the definition, classification, and pathogenesis of cervical vertigo to clarify its pathological basis. Subsequently, the article deeply discussed the principles and methods of acupuncture and moxibustion and massage in the treatment of cervical vertigo, and analyzed the theoretical basis and specific operating steps of the two traditional Chinese medicine treatment methods. On this basis, this paper further discussed the clinical study of acupuncture and moxibustion combined with massage in the treatment of cervical vertigo, including the study design, implementation process, and analysis and discussion of the results. The research results show that the combination of acupuncture and moxibustion and massage has a significant effect in the treatment of cervical vertigo, and can significantly improve the symptoms and quality of life of patients. This study provides a new perspective and method for the clinical treatment of cervical vertigo, which is of great significance for pro
目的:基于R语言探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的组穴规律,为针灸治疗该病提供选穴依据。方法:检索“知网”、“维普”、“万方”、“中国生物医学文献数据库”中治疗骨质疏松性压缩性骨折的相关文献,并用采用Excel软件进行统计,利用R语言进行频数统计、关联规则分析、聚类分析。结果:共纳入52个处方,共包含穴位39个,选穴频数前10的穴位为:肾俞、腰阳关、命门、足三里、大肠俞、委中、阳陵泉、腰椎夹脊、三阴交、环跳;穴位归经以膀胱经为主,特定穴以背俞穴为主;关联规则分析显示以百会、脾俞、至阳、肝俞、上髎、气海、关元、大椎穴为主的核心组合;层次聚类分析得到4类、15类穴位组合。结论:探讨针灸结合其他疗法治疗骨质疏松性椎体压缩性骨折的临床组穴规律,为临床治疗骨质疏松性椎体压缩性骨折提供选穴思路。Objective: To explore the acupuncture combination therapy regimen for osteoporotic vertebral compression fractures and provide acupoint selection guidelines based on R language. Methods: The relevant literature on the treatment of osteoporotic vertebral compression fractures was searched on “CNKI”, “VIP”, “Wanfang”, and “China Biomedical Literature Database”, and statistical analysis was conducted using Excel software. Frequency statistics, association rule analysis, and clustering analysis were conducted using R language. Results: A total of 52 prescriptions were included, containing 39 acupoints. The top 10 acupoints with the highest frequency of selection were: Shenshu, Yaoyangguan, Mingmen, Zusanli, Dachangshu, Weizhong, Yanglingquan, Yaozhuijiaji, Sanyinjiao, and Huantiao;the main meridians of the acupoints were the Bladder Meridian;the specific points were mainly back shu points;the core combination of association rule analysis was mainly Baihui, Bladder 20, Zhiyang, Shangliao, Qihai, Guanyuan, and Dazhui;the c
