胶质肉瘤(gliosarcoma, GS)是指包含胶质母细胞瘤和肉瘤两种混合成分的原发中枢神经系统恶性肿瘤。在中枢神经系统肿瘤的广泛分类体系中,GS明确归属于胶质母细胞瘤的一个特殊亚型,具有胶质和间叶组织双向分化的恶性肿瘤,单克隆起源。这一归类强调了其独特的病理特征和恶性程度,即该肿瘤具有显著的恶性肿瘤特性。在临床上,GS是一种罕见的高度恶性中枢神经系统肿瘤,被世界卫生组织(WHO)分类为IV级,其发病率在多形性胶质母细胞瘤中约占1.8%至8%。GS作为一种罕见的中枢神经系统恶性肿瘤,其影像学特征对于临床诊断和治疗规划至关重要。本文通过对一例GS患者的前后两次的影像学特征表现进行分析,并结合文献复习,探讨了GS的影像学特点及其在诊断和鉴别诊断中的价值。旨在提高本疾病的影像成像诊断水平及经验。Gliosarcoma (GS) is a primary central nervous system malignant tumor that contains both glioblastoma and sarcoma components. Within the extensive classification system of central nervous system tumors, GS is distinctly categorized as a special subtype of glioblastoma, a malignant tumor with bidirectional differentiation of glial and mesenchymal tissues, and monoclonal origin. This classification emphasizes its unique pathological characteristics and degree of malignancy, that is, the tumor has significant malignant tumor characteristics. Clinically, GS is a rare and highly malignant central nervous system tumor, classified by the World Health Organization (WHO) as grade IV, with an incidence rate of about 1.8% to 8% in glioblastoma multiforme. GS, as a rare malignant tumor of the central nervous system, its imaging characteristics are crucial for clinical diagnosis and treatment planning. This article analyzes the imaging features of a GS patient in two instances and reviews the literature to explore the imaging features of GS and their value in diagnosis and differential diagnosis
