急性横贯性脊髓炎是一种以脊髓局灶性炎症为特征的脊髓疾病,虽然少见,但可能遗留严重的神经系统后遗症。近年来,随着脱髓鞘相关抗体的发现,对该病的认识也不断提高。因此,本文拟通过对急性横贯性脊髓炎相关文献的分析和总结,探讨急性横贯性脊髓炎的流行病学、发病机制、临床表现、诊断方法、鉴别诊断、治疗和预后,旨在为临床医生提供对该病的更好认识,指导临床的早期规范化诊断、针对性治疗,最终改善患者预后。Acute transverse myelitis is a spinal cord disease characterized by focal inflammation of the spinal cord. Although it is rare, it may leave serious neurological sequelae. In recent years, with the discovery of demyelinating-related antibodies, the understanding of this disease has been continuously improved. Therefore, this article aims to analyze and summarize the relevant literature on acute transverse myelitis to explore its epidemiology, pathogenesis, clinical manifestations, diagnostic methods, differential diagnosis, treatment, and prognosis. The goal is to provide clinicians with a better understanding of the disease and guide early standardized diagnosis and targeted treatment in clinical practice, ultimately improving the prognosis of patients.