[Objective] The aim was to study on germination and expression of α-amy- lase of KF0680-1 and KF0680-2 (cultivars of sweet sorghum) under salt stress. [Method] In the research, KF0680-1 and KF0680-2, cultivars of sweet sorghum, were used to measure related indices of germination and expression of co-amylase to discuss effect of salt stress on two cultivars. [Result] Germination of sweet sorghum would be promoted if treated with salt in low concentration and inhibited if treated in high concentration. In the latter condition, roots and seedlings were smaller than that of control group in length, but expression of s-amylase in the two cultivars was pro- moted under proper salt stress. [Conclusion] The research indicates that KF0680-1 and KF0680-2 are inhibited in growth by salt stress and the latter is stronger in salt resis- tance than the former under low salt concentration. In addition, expression of α-amy- lase could be promoted by salt in proper volume. The results provide references for selection of sweet sorghum which could be planted in northwestern areas.