To observe any malignancy sufferer's homocysteine level in plasma, and to study homoeysteine had the influence upon malignancy happened. Methods By Fluorescence Polarization Immunoassay(FPIA) technology and Electrochemiluinescence Immuoassay technology, to mensurate and assay between the tumor marker and the tHey in 78 patients with malignancy and 50 normal person. Results Malignancy sufferer's tumor marker and homocysteine level prominence increase, but not the diseiphnarian crease did changed the relationship between the tHey and the tumor marker. Conclusion The tHey innot influence malignancy results, but accelerated to influence
To study the serum changed of 6 tumor markers in pancreatic cancer patients, apply pacreatic cancer clinical diagnosis. Methods Use the Electrochemiluinescence to determine quantitatively the 6 tumor markers, in eluding alpha-fetoprotein (AFP), careinoembryonic antigen (CEA), carcinoembryonic antigen19-9 (CA19-9),carcinoembryonic antigen125 (CA125), carcinoembryonie antigenl5-3 (CA15-3) and careinoembryonic antigen72-4(CA72-4) in the serum of 42 patients with pancreatic cancer and 45 healthy persons as eonwal, Results AFP (3.71+2.92) ng/ml,CEA(2.3+ 1.6)ng/ml, CA19-9(12.8+11.4)U/ml, CA125(14.92+12.01)U/ml, CA15-3(10.3 +9.1 ) U/ml and CAn-4 (6.5+3.2) U/ml were in healthy person, CA19-9, CEA and CA125 was raised higher in panereatie eaneer patients then healthy persons, CA19-9 Was statistically signifeant (P <0.01).CEA and CA125 wers statistieally signifeant (P<0.05). The positive rate of the allied detection was 95.2%, the speeifieity was 82.2%, and the available was 88.5%. But the same of AFP, CA15-3 andCA125 weren't statistieally singifeant between panereatie eaneer patients and healthy persons(P>0.05).Conelusions The CA19-9 was better sumor markers of panereatie eaneer. The allied detection of CA19-9,CEA and CA125 were better to use elinieal diagnosis, and AFP, CA15-3 and CA72-4 were no better to useelinieal diagnosis.
