[Objective] The paper aimed to reflect the spatial pattern and temporal and spatial evolution characteristics, the differences between inter-regional tourism economy was measured from the quality aspect, which provided a reference for the local governments in the future tourism development. [Method] Using the location entropy methods, three time periods side of tourism-related date of 2000, 2005, 2007 were selected, from the angle of the spatial pattern and the evolution of the differences within the different scales, the spatial and temporal evolution characteristics of the economic development level of Jiangsu were analysed. [Result] The results showed that from the aspect of spatial evolution pattern, as time goes on, the economic development of Jiangsu tourism has experienced morphological evolution of concentration- dispersion decrease-stability; when it comes to the development of the tourism economy, in recent years, the overall gap between the tourism economy in Jiangsu did not widen, the gap mainly led by the region one after another. According to their volatility, it will be divided into four categories: A Stable type (Wuxi, Xuzhou, Lianyungang and Taizhou), B Increasing type (Huai’an), C Fluctuations type (Nanjing, Changzhou, Suzhou and Yangzhou) and D Depression type (Nantong, Yancheng, Zhenjiang and Suqian). [Conclusion] Location entropy was quoted into tourism economic analysis, the method was simple and easy to understand, the result was accurate and convincing, which provided a reference for travel economic development and investment decision-making of Jiangsu.