To investigate the chemical constituents of a South China Sea gorgonian Menella sp., the isolation of ingredients was performed by solvent extraction and repeated chromatography on silica gel, Sephadex LH-20 and preparative TLC. The structures of isolated compounds were determined by spectroscopic analysis and comparison of 1H and 13C NMR data with those reported inliteratures. Three subergorane sesquiterpenoids and one suberosane sesquiterpenoid were isolated. Their structures were identified as subergorgic acid （1）, subergorgic acid methyl ester （2）, 2β-hydroxyl subergorgic acid methyl ester （3）, and suberosenol A （4）. All compounds were isolated from the genus Menella for the first time.
