Rice restorer Qianhui 5819 bred by Guizhou Institute of Crop Germplasm Resources and cytoplasm male sterile（CMS） line Anfeng A bred by Rice Research Institute, Fujian Academy of Agricultural Sciences were used to develop three-line mid-season indica hybrid rice Anyou 5819. Anyou 5819 was examined and approved by Guizhou Crop Variety Approval Committee in June 2014（No.2014013 validated in Guizhou）. The average yield of the combination in Guizhou regional test of hybrid rice in 2012 and 2013 were 8 839.05 kg/hm^2 and 9 693.90 kg/hm^2, respectively. The yields increased 8.66% and 8.80% respectively compared with the control Xiangzaoyou 2017. The yields of 15 points among 16 points during the two years were increased. In addition the average yield in Guizhou production test of early-maturing hybrid rice in 2013 was 8 772.15 kg/hm^2. It increased 2.31% compared with the control Xiangzaoyou 2017. In General, Anyou 5819 has high yield,disease resistance, good quality and moderate growth period, which is suitable for the rice cropping area with middle and high altitude in Guizhou.
