The condensation product from D-glucose and N,N’-diamino-diphenyl-methan was prepared and the optimal synthetic conditions were determined;D -Glucose and N,N’-Diamino-diphenyl-methane(1mol∶1mol)were dissolved in anhydrous methanol,reflux raction 25h,yield 53.3%,purity 99.4%,and its structure was characterized by elemental analysis,IR and NMR spectroscopy.The hydrolysis of the condensation product was studied,and results show that the condensation reaction was at equilibrium,and the influence of time and the N,N’-diamino-dimphenyl-methan concentration in water on the hydrolysis were researched.