Radiation damage of Lu2SiO5:Ce (LSO:Ce) crystals was investigated through intense UV light. An absorption band at 435 nm was observed in the transmission spectrum of the damaged LSO:Ce crystal, similar to that of absorption band caused by gamma ray irradiation. GDMS analysis for LSO:Ce crystals revealed the existence of impurities, such as Yb in the crystals. The impurities might be responsible for the optical absorption of the color center and the radiation center.