In a microcosm system where Elodea nuttallii and Bisphenol A (BPA) coexist, with the help of Liquid chromatography-mass spectrometer (LC-MS) and gas chromatography-mass spectrometer (GC-MS), the dynamics of phytodegradation of BPA with concentration 1-20 mg/L and the products of phytodegradation was studied. Antioxidation activity and phospholipids fatty acids were measured to evaluate the effects of BPA on E.nuttallii. The results showed that the half life period of phytodegradation of BPA was less than 15 days. 2-(4-hydroxypheny)-2-(3,4-o-dihydroxypheny) propane and 2, 2-bis(4-hydroxypheny) propyl alcohol were identified to be as two possible products of BPA. The peroxidase (POD) activity of E.nuttallii decreased by 50% to 100% compared with that controlled at the end of the experiment. The fatty acid methanol esters (FAMEs) changed obviously too. It showed that oxidation stress and membrane damage would be the two effcting aspects of BPA on E.nuttallii.