The economy of China has been developing fast after the beginning of the new century, but the 31 provinces or municipalities (excluding Hong Kong, Taiwan and Macao) develop disparately. So, finding an appropriate way to analyze and compare the economic situations of various regions is of great significance for the balanced development of the east coastal area and the hinterland. With the DEA method, on the basis of regionalism, this paper analyzes various regions of China, and gets the conclusion that the effective proportion of DEA of the coastal developed areas is relatively higher, and the extremely tittle foreign investment makes the relative efficiency of DEA of frontier areas pretty high. In addition, through the analysis parameters of the regions where DEA is relatively ineffective, this paper points out that the surplus labor force is the most influential factor, and the spare foreign investment is the main reason for the lack of efficiency of relatively developed regions.